Step 1. Create a segment with the group of contacts you want to exclude.
In this case, we will exclude those guests who like to travel with partner/spouse.
Step 2. Save the segment with the name you want and that you can remember at a later time. In this case we use the name "Test".
Step 3. Create a new segment or open the segment in which you want to exclude guests that like to travel with partner/spouse.
Step 4. Save your segment.